Proprietary rights to cell lines: Roche pays up

Who pays to clean up livestock waste?

MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes. It provides detailed all-atom contact analysis of any steric problems within the molecules as well as updated dihedralangle diagnostics, and it can calculate and display the H-bond and van der Waals contacts in the interfaces between components. An integral step in ...

Proprietary rights and the norms of science in biotechnology research.

Protecting Intellectual Proprietary Rights through Secure Interactive Contract Negotiation

Protection of Intellectual Proprietary Rights is currently one of the most important barriers to electronic commerce of digital contents over networks. Authors and content providers understand the immense advantages of the digital world but show some reserve. However, technologies and techniques to protect IPR in digital content exist, their deployment in a coherent way is still in an early sta...

Celecoxib Up Regulates the Expression of Drug Efflux Transporter ABCG2 in Breast Cancer Cell Lines

Elevated expression of the drug efflux transporter ABCG2 seems to correlate with multidrug resistance of cancer cells. Specific COX-2 inhibitor celecoxib has been shown to enhance the sensitivity of cancer cells to anticancer drugs. To clarify whether ABCG2 inhibition is involved in the sensitizing effect of celecoxib, we investigated whether the expression of ABCG2 in breast cancer cell lines ...

Celecoxib Up Regulates the Expression of Drug Efflux Transporter ABCG2 in Breast Cancer Cell Lines

Elevated expression of the drug efflux transporter ABCG2 seems to correlate with multidrug resistance of cancer cells. Specific COX-2 inhibitor celecoxib has been shown to enhance the sensitivity of cancer cells to anticancer drugs. To clarify whether ABCG2 inhibition is involved in the sensitizing effect of celecoxib, we investigated whether the expression of ABCG2 in breast cancer cell lines ...